It really matters whether people are working on generating clean energy or improving transportation or making the Internet work better and all those things. And small groups of people can have a really huge impact.
I think the best architecture comes from a synthesis of all the elements that separately comprise a building: the structure that holds it up; the services that allow it to function; its ecology; the quality of natural light; the symbolism of the form; the relationship of the building to the skyline or the streetscape; and, perhaps most importantly, the client's vision and the user's needs.